Clinical Trials

Research News

Meta-Analysis Finds Benefits of Adjuvant Bisphosphonates for Postmenopausal Breast Cancer

September 8th, 2015

Bisphosphonates can reduce the rate of breast cancer recurrence in bone, according to a meta-analysis of randomized trials of bisphosphonates as adjuvant therapy for women with early-stage breast cancer.
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Palbociclib Improves Survival in Women with Hormone Receptor-Positive Metastatic Breast Cancer

July 23rd, 2015

An interim analysis of the PALOMA3 trial shows that palbociclib plus fulvestrant extends the progression-free survival of some women with hormone receptor-positive metastatic breast cancer.
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Pembrolizumab Improves Progression-Free Survival in Patients with Ipilimumab-Resistant Melanoma

July 19th, 2015

Results from the KEYNOTE-002 clinical trial show that pembrolizumab improves progression-free survival in patients with ipilimumab-resistant melanoma.
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Nivolumab-Based Treatments Delay Progression of Advanced Melanoma

June 25th, 2015

In an international, double-blind, randomized phase III trial, the combination of nivolumab and ipilimumab improved progression-free survival compared with ipilimumab alone for patients with advanced melanoma.
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Pembrolizumab Improves Overall Survival in Patients with Advanced Melanoma

May 25th, 2015

In a randomized phase III study, pembrolizumab (Keytruda®) improved survival in patients with advanced melanoma compared with Ipilimumab (Yervoy®).
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Gardasil 9 Vaccine Protects against Additional HPV Types

March 1st, 2015

In a large randomized clinical trial, a new human papillomavirus (HPV) vaccine effectively prevented infection and disease caused by nine high-risk HPV types, including seven types that cause cervical and other cancers—five of which were not covered by the previously available HPV vaccines—and two types that cause genital warts.
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Gardasil 9 Vaccine Protects against Additional HPV Types

March 1st, 2015

In a large randomized clinical trial, a new human papillomavirus (HPV) vaccine effectively prevented infection and disease caused by nine high-risk HPV types, including seven types that cause cervical and other cancers—five of which were not covered by the previously available HPV vaccines—and two types that cause genital warts.
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Gardasil 9 Vaccine Protects against Additional HPV Types

March 1st, 2015

In a large randomized clinical trial, a new human papillomavirus (HPV) vaccine effectively prevented infection and disease caused by nine high-risk HPV types, including seven types that cause cervical and other cancers—five of which were not covered by the previously available HPV vaccines—and two types that cause genital warts.
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Three-Drug Combination Benefits Some Patients with Relapsed Multiple Myeloma

January 8th, 2015

Interim results from an international, randomized phase III trial suggest that adding carfilzomib (Kyprolis®) to a standard treatment improves outcomes for patients with multiple myeloma whose cancer has relapsed. Participants in the study who received carfilzomib plus lenalidomide (Revlimid®) and dexamethasone lived a median of 8.7 months longer without the disease getting worse than patients who received lenalidomide and dexamethasone alone.
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Three-Drug Combination Benefits Some Patients with Relapsed Multiple Myeloma

January 8th, 2015

Interim results from an international, randomized phase III trial suggest that adding carfilzomib (Kyprolis®) to a standard treatment improves outcomes for patients with multiple myeloma whose cancer has relapsed. Participants in the study who received carfilzomib plus lenalidomide (Revlimid®) and dexamethasone lived a median of 8.7 months longer without the disease getting worse than patients who received lenalidomide and dexamethasone alone.
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