At Shenandoah Oncology, research is an integral part of our comprehensive efforts to provide cancer patients in our community with access to the latest and most advanced therapies and treatment options. As a member of US Oncology Research and as a clinical research affiliate of VCU Massey Cancer Center, we are pleased to share this list of clinical trials currently enrolling at our practice.
BREAST CANCER - ADJUVANT
Phase 4, Observational Breast Cancer Study for stage I-III hormone receptor-positive (HR+) breast cancer that has taken adjuvant endocrine therapy for 4-7 years. Breast Cancer Index (BCI) Registry Study. Click here to learn more
BREAST CANCER – METASTATIC
Phase 3, double-blind, randomized, placebo-controlled study of abemaciclib + fulvestrant versus placebo + fulvestrant for patients with hormone receptor-positive, HER2 negative, who have progressed after prior treatment with CDK4 & 6 inhibitor and endocrine therapy. Click here to learn more
Phase 3, randomized, double-bind study of taxane/trastuzumab/pertuzumab with atezolizumab or placebo in first-line HER2-Positive metastatic breast cancer. Click here to learn more
Phase 3, randomized, double-blind study of Vitamin D3 supplementation in patients with previously untreated metastatic colorectal cancer. Click here to learn more
Phase 2/3, randomized, double-blind, placebo-controlled study of duloxetine to prevent oxaliplatin-induced chemotherapy-induced peripheral neuropathy. Click here to learn more
LUNG – METASTATIC
Phase 3, open-label, randomized study of sacituzumab govitecan versus docetaxel in patients with advanced or metastatic non-small cell lung cancer with progression on or after platinum-based chemotherapy and anti-PD-1/PD-L1 immunotherapy. Click here to learn more
Detecting cancers earlier through elective plasma-based CancerSEEK testing. Patients age 50 years old or greater with untreated solid tumors will undergo one-time blood draw to obtain clinically characterized, whole blood specimens from cancer subjects to develop and refine assays for cancer in the blood.