Open Trials

At Shenandoah Oncology, research is an integral part of our comprehensive efforts to provide cancer patients in our community with access to the latest and most advanced therapies and treatment options.  With collaborations with Sarah Cannon Research Institute (SCRI) and VCU Massey Cancer Center, we are pleased to share this list of clinical trials currently enrolling at our practice.

BREAST CANCER - ADJUVANT

USOR 22-326: Phase 3, open-label, randomized study to assess the efficacy and safety of camizestrant (AZD9833, a next-generation, oral selective estrogen receptor degrader) vs standard endocrine therapy (aromatase inhibitor or tamoxifen) as adjuvant treatment for patients with ER+/HER2- early breast cancer and an intermediate-high or high risk of recurrence who have completed definitive locoregional treatment and have no evidence of disease (CAMBRIA-2). Click here to learn more

A012301: A randomized, phase 3 clinical trial of low‐dose tamoxifen for selected patients with molecular low-risk early‐stage breast cancer. Click here to learn more

HEAD & NECK

USOR 24-004: A phase 3 open-label, randomized, controlled study to evaluate the efficacy and safety of petosemtamab compared with investigator's choice monotherapy treatment in previously treated patients with incurable, metastatic/recurrent head and neck squamous cell carcinoma. Click here to learn more

LUNG

USOR 23-235: Phase 2 Study of EIK1001 in Combination with Pembrolizumab and Chemotherapy in Patients with Stage 4 Non-Small Cell Lung Cancer. Click here to learn more

PREVENTION

URCC 19185: Multicenter, randomized trial comparing Brief Behavioral Therapy for Cancer-Related Insomnia (BBT-CI) vs. Healthy Eating Education Learning (HEAL) for treatment of insomnia. Click here to learn more

URCC 22063: Longitudinal Observational Trial to Uncover Subtypes of Cancer Cachexia. Click here to learn more

WF-2304-172401: Complementary Options for Symptom Management In Cancer (COSMIC): Assessing Benefits and Harms of Cannabis and Cannabinoid Use Among a Cohort of Cancer Patients Treated in Community Oncology Clinics. Click here to learn more